Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1027
Gene Symbol: CDKN1B
CDKN1B 		0.100 Biomarker disease HPO
Entrez Id: 4221
Gene Symbol: MEN1
MEN1 		0.100 Biomarker disease HPO
Entrez Id: 1030
Gene Symbol: CDKN2B
CDKN2B 		0.100 Biomarker disease HPO
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A 		0.100 Biomarker disease HPO
Entrez Id: 1031
Gene Symbol: CDKN2C
CDKN2C 		0.100 Biomarker disease HPO
Entrez Id: 3815
Gene Symbol: KIT
KIT 		0.170 AlteredExpression disease LHGDN Absence of gene mutations in KIT-positive thymic epithelial tumors. 18486988 2008
Entrez Id: 1956
Gene Symbol: EGFR
EGFR 		0.100 GeneticVariation disease LHGDN EGFR protein was expressed in 71% of the thymomas and 53% of the thymic carcinomas. 18448188 2008
Entrez Id: 1493
Gene Symbol: CTLA4
CTLA4 		0.060 GeneticVariation disease LHGDN The unusual disease association with a CTLA4high genotype implies a unique pathogenesis of paraneoplastic MG, with high CTLA4 levels possibly supporting the nontolerogenic selection of CD4+ T cells in MG-associated thymomas. 16178018 2005
Entrez Id: 8456
Gene Symbol: FOXN1
FOXN1 		0.040 Biomarker disease LHGDN Foxn1 was diffusely expressed in nuclear staining in all cases of type B thymoma and all but 1 case of type A thymoma, whereas the expression was generally focal in thymic carcinoma (76%). 17592270 2007
Entrez Id: 26191
Gene Symbol: PTPN22
PTPN22 		0.030 GeneticVariation disease LHGDN Association of the PTPN22*R620W polymorphism with autoimmune myasthenia gravis. 16437561 2006
Entrez Id: 2597
Gene Symbol: GAPDH
GAPDH 		0.030 AlteredExpression disease LHGDN Cten mRNA expression is correlated with tumor progression in thymoma. 15001839 2004
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.020 AlteredExpression disease LHGDN Furthermore, additional cases of thymomas and thymic carcinomas were analyzed by COX-2 Western immunoblot analysis and were compared to normal thymi. 16823844 2006
Entrez Id: 84951
Gene Symbol: TNS4
TNS4 		0.010 AlteredExpression disease LHGDN Cten mRNA expression is correlated with tumor progression in thymoma. 15001839 2004
Entrez Id: 3593
Gene Symbol: IL12B
IL12B 		0.010 AlteredExpression disease LHGDN Elevation of IL-12 p40 and its antibody in myasthenia gravis with thymoma. 16574246 2006
Entrez Id: 1145
Gene Symbol: CHRNE
CHRNE 		0.010 AlteredExpression disease LHGDN The greater abundance of mRNA for AChR epsilon-subunit than for other subunits suggests that the AChR epsilon-subunit may play a distinctive role in autosensitization in MG-associated thymomas, particularly those of type A or AB. 18657869 2008
Entrez Id: 8626
Gene Symbol: TP63
TP63 		0.010 Biomarker disease LHGDN All thymomas (including thymic carcinomas) were positive for p63 regardless of type. 17276940 2007
Entrez Id: 3880
Gene Symbol: KRT19
KRT19 		0.010 AlteredExpression disease LHGDN Multimodality therapy and significance of serum CYFRA21-1 for thymic carcinoma. 15870932 2005
Entrez Id: 4065
Gene Symbol: LY75
LY75 		0.010 Biomarker disease LHGDN CD205 cytoplasmic expression in the form of coarse granular staining with membranous accentuation was strong and diffuse in all cases of type B thymoma (100%), and a majority of type A thymoma (89%), and focal with variable intensity in thymic carcinoma (59%). 17592270 2007
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.360 Biomarker disease CTD_human A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors. 24974848 2014
Entrez Id: 8314
Gene Symbol: BAP1
BAP1 		0.310 Biomarker disease CTD_human A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors. 24974848 2014
Entrez Id: 1029
Gene Symbol: CDKN2A
CDKN2A 		0.310 Biomarker disease CTD_human A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors. 24974848 2014
Entrez Id: 1540
Gene Symbol: CYLD
CYLD 		0.300 Biomarker disease CTD_human A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors. 24974848 2014
Entrez Id: 55193
Gene Symbol: PBRM1
PBRM1 		0.300 Biomarker disease CTD_human A specific missense mutation in GTF2I occurs at high frequency in thymic epithelial tumors. 24974848 2014
Entrez Id: 3815
Gene Symbol: KIT
KIT 		0.170 CausalMutation disease CLINVAR Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation. 15930355 2005
Entrez Id: 3815
Gene Symbol: KIT
KIT 		0.170 CausalMutation disease CLINVAR Promising efficacy of sorafenib in a relapsed thymic carcinoma with C-KIT exon 11 deletion mutation. 20970876 2011